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Biomimetic peptides in skincare

BIOMIMETIC MULTIPEPTIDE COMPLEX IN SKINCARE

Peptides are short chains of amino acids that are the building blocks of certain proteins needed by the skin, like collagen and elastin. Biomimetic skincare incorporates ingredients naturally found in skin such as water, lipids, proteins, sugars and mineral salts. In skin care, biomimetic peptides can be found in targeted treatments like facial formulas to help reduce the appearance of skin aging.

Peptides are chemical messengers that tell our cells what to do. All peptides are made up of amino acids, which are used by the skin to build proteins such as collagen, elastin and keratin. These substances are what hold the skin together and keep it firm. Peptides can also control factors that contribute to skin tone, sensitivity, hormonal activity, and more.

Biomimetic peptides can be added to cosmetic formulas to achieve specific results like wrinkle reduction and anti-aging.

What is XEP™-018?

XEP™-018 is a biomimetic peptide obtained from the venom of the sea snail (cone snail), one of the most dangerous inhabitants of our planet. Today it is one of the most active botulinum peptides.

XEP®-018 is a muscle relaxant naturally present in the venom of the sea snail Conus consors that lives in the Pacific Ocean. This predatory snail uses this to immobilize its prey rapidly & efficiently. It is a safe and highly potent ingredient.

In a dose-dependent manner, mu-conotoxin acts specifically on the neuromuscular channel Nav1.4, blocking the electrical impulse that causes muscle contraction. As a result, the muscle relaxes, facial wrinkles are smoothed out, while natural facial expressions and sensitivity are preserved. 5% of the substance remains in neuromuscular signal contacts.

It is recommended for skin care products.

XEP™-018 relaxes the muscle, but does not block it completely, ensuring a natural result. Acts as an immediate muscle relaxant, giving a smooth appearance to the skin, smoothing the length and depth of facial wrinkles. It is an excellent alternative to “beauty injections”.

Contrary to botulinum toxin, the XEP®-018 is small enough to penetrate the skin and thus doesn’t need to be injected to exert its muscle relaxant activity.

XEP-018 naturally relaxes facial muscles and eliminates wrinkles as it acts on a nerve synapse rather than interfering with the normal functioning of the nervous system, ultimately offering a non-surgical cosmetic treatment.

According to safety, toxicology and skin irritation studies conducted in laboratories:

• does not cause skin irritation

• does not cause eye irritation

• non-cytotoxic and non-mutagenic

• non-phototoxic

• hypoallergenic and not classified as a sensitizer

XEP™-018 Benefits:

• High stability

• Narrow focus of action

• Deeper penetration into the skin compared to linear peptides

What is Snap-8™ peptide?

SNAP 8™ is the ultimate preventative measure against fine lines and wrinkles. This powerful skin-smoothing peptide helps muscles relax to minimize the appearance of expression lines around the eyes and forehead.

This safe alternative to Botox works by inhibiting acetylcholine, reducing muscle contractions and visibly reducing wrinkles.

But that’s not all – SNAP 8™ is also a humectant that helps strengthen and protect the skin’s natural barrier from premature aging by preventing moisture loss and pollution damage. It is a non-invasive alternative to botulinum toxin injections, inhibiting the formation of the SNARE complex is an effective strategy to reduce the release of neurotransmitters and thereby regulate muscle contraction.

Snap-8™ is designed as an analogue of the N-terminal of SNAP-25 and competes with this protein for a place in the SNARE complex, thereby destabilizing           the SNARE complex and reducing the release of neurotransmitters.

Benefits:

 • Less wrinkles caused by    muscle contraction

 • Non-invasive alternative to botulinum toxin injections

 • Relaxation of fine    lines and wrinkles for smoother skin

 • Slow down  the transformation of fine lines into wrinkles

 • Smooth existing wrinkles    and prevent    the appearance of new ones

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